THE POS88 SLOT DIARIES

, 2006; Sawaya and Kraut, 1997; Figure 1—figure supplement one), we expected the mutational landscape of DHFR being constrained with the prerequisite to adopt these distinct conformations. Moreover, prior work experienced instructed DHFR is impacted by mobile constraints for instance protein high-quality Command (Bershtein et al., 2013) as well